NJ, Belle Clipboard, Search History, and several other advanced features are temporarily unavailable.  DA, Nuttleman Nevertheless, 88.6% of patients reported 1 or more symptoms (mild to severe) a median of 4.7 years after RYGB surgery.  WR, Caldwell The media has reported extensively on weight-loss surgery for obesity today, with The Daily Telegraph saying that the number of gastric bypass … We tabulated characteristics of the cohort that underwent RYGB surgery and the comparison cohort and tabulated the prevalence and severity of symptoms.  RL, Davidson Dumping syndrome is a well-known side effect of laparoscopic gastric bypass (LRYGB), and it is commonly believed that dumping syndrome is less likely … Data analysis was conducted from September 1, 2014, to June 25, 2015. Knowledge of possible predictors is important to prevent symptoms related to RYGB surgery after the procedure. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. The main strengths of our study are its large size, population-based sample, relatively long time frame, and examination of a broad range of symptoms and demographic factors. Dumping and hypoglycemia alone accounted for only 24 (1.7%) of the total health care contacts.  et al. Median time since RYGB surgery was 4.7 years. Quiz Ref IDInpatient hospitalizations owing to any symptom after surgery were reported by 416 patients (29.1%) in those who underwent RYGB surgery vs 6 individuals (6.7%) in the comparison cohort (Table 2). Many of the surgical procedures performed on the massive weight loss patient are complex and labor-intensive. Surgery and the postoperative period were unremarkable; during the first year after surgery, she lost ∼80 pounds. Little literature is available on how frequently patients who have undergone gastric bypass surgery receive body contouring surgery. Thirty-five patients did not answer this question.  TL.  AV, Galvão Neto As seen in Table 1, the comparison cohort was matched on current body mass index (29.4) and sex (22.5% male), yet it was slightly younger (mean age, 37.7 years). Patients who underwent RYGB surgery were grouped according to the number of symptoms leading to health care contact (0, 1, 2, 3, ≥4 symptoms). COVID-19 is an emerging, rapidly evolving situation.  SH, In those undergoing RYGB surgery, 955 of 1314 patients (72.7%) had an MCS below the cutoff for depression risk; in the comparison cohort, 66 of 85 individuals (77.6%) had an MCS below the cutoff for depression risk.41 The negative effect of symptoms that occur after RYGB surgery on the patients’ reported QoL suggests that screening for depression might be beneficial among patients undergoing RYGB surgery, especially among patients with several symptoms. Predictors of symptoms included young age, female sex, smoking, and experiencing symptoms before RYGB surgery. All Rights Reserved, Challenges in Clinical Electrocardiography, Clinical Implications of Basic Neuroscience, Health Care Economics, Insurance, Payment, Scientific Discovery and the Future of Medicine, United States Preventive Services Task Force, 2016;151(6):504-511. doi:10.1001/jamasurg.2015.5110.  KJ, Greenland A survey was conducted from March 3 to July 31, 2014, among 2238 patients who underwent RYGB surgery between January 1, 2006, and December 31, 2011, in the Central Denmark Region.  K.  The effect of smoking on bariatric surgical outcomes.Â, Alamanda 2020 Mar;30(3):924-930. doi: 10.1007/s11695-019-04298-1. Gribsholt SB, Pedersen AM, Svensson E, Thomsen RW, Richelsen B. Quiz Ref IDCommon surgical symptoms after RYGB surgery include gallstones (7%-16% after 18-26 months’ follow-up)6,7 and kidney stones (≤8% after 19-42 months’ follow-up).8 Well-known medical and nutritional symptoms include dumping syndrome (12%-42% after 1-2 years),9-11 hypoglycemia (0.2% of patients were hospitalized within 0-20 years),12 diarrhea (18% of patients with anal leakage of stool potentially provoked by diarrhea after 2 years),13 peripheral neuropathy (16% of patients, with unknown follow-up period),14 and anemia (23%-47% after 24-48 months).15-17 Commonly observed symptoms in clinical practice, such as abdominal pain and fatigue, are sparsely described in the literature on RYGB surgery despite the importance of such symptoms for patients’ functional status and QoL.18,19 Thus, a large population-based study with long-term follow-up of patients who had undergone RYGB surgery, providing a more comprehensive examination of symptom prevalence, is warranted.  TM, English Common surgical symptoms after RYGB surgery include gallstones (7%-16% after 18-26 months’ follow-up).  B, Ware Gribsholt, A.M. Pedersen, E. Svensson, et al.Prevalence of self-reported symptoms after gastric bypass surgery for obesity JAMA Surg, 151 (6) …  HJ, Kellum  Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity.Â, Gonzalez  Patient Well-being After Roux-en-Y Gastric Bypass Surgery vs Before Surgery, Table 1. We defined mild dumping as a score of 18 to 35 (symptomatic to the patient), moderate dumping as a score of 36 to 44 (likely to lead to contact with primary care), and severe dumping as a score of 45 or more (likely to lead to contact with secondary care). Methods:  S, Thorsteinsson RESULTS: There were 90 open gastric Conclusions:  DJ, Ho More of the nonrespondents were male; since male sex was associated with a lower risk of symptoms, we would expect an even larger sex difference than what we observed. Heart And Gastric Bypass Information (SCROLL DOWN FOR GASTRIC BYPASS) Heart Bypass Surgery Statistics - 2013 Update Bypass surgery is a major surgery … More nonrespondents than respondents underwent RYGB surgery during 2010-2011, but there were no significant differences in PRs at time since surgery (eTable 4 in the Supplement).  The Danish Civil Registration System.Â, Nguyen-Nielsen In contrast to 3 previous studies,20,21,23 we found that younger age was associated with a higher prevalence of symptoms. We hypothesized that alcohol metabolism in the postoperative gastric bypass … The Central Denmark Region has a population of approximately 1.27 million people.  Postoperative complications in bariatric surgery using age and BMI stratification: a study using ACS-NSQIP data.Â, Haskins Prevalence ratios (PRs) of symptoms associated with different predictors were computed.  et al. Epub 2008 Jun 17.  C, Capuron The Prevalence of Anastomotic Stenosis Post Laparoscopic Gastric Bypass Surgery and the Efficacy of Medical Nutrition Therapy Bariatric surgery has … 2020 Jun 24;8(6):e2874. We assessed QoL using the Mental Composite score (MCS) (6 items) and the Physical Composite score (PCS) (6 items) of the 12-Item Short-Form Health Survey (SF-12), which has been validated in the general Danish population.35 The scores for all items are summed and transformed into a scale from 0 to 100 (0 indicates poorest possible health state; 100, best possible health state).  M, Moretto Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Prevalence and Predictors of Asymptomatic Liver Disease in Patients Undergoing Gastric Bypass Surgery… Contacts with the health care system owing to routine follow-up visits after RYGB surgery were not included in this questionnaire.  E.  Nationwide cohort study of post-gastric bypass hypoglycaemia including 5,040 patients undergoing surgery for obesity in 1986-2006 in Sweden.Â, Søvik Prevalence estimates to date have been based on hospital admission data although many patients with hypoglycemia are not hospitalized.12. Critical revision of the manuscript for important intellectual content: Svensson, Thomsen, Richelsen. Since some of the symptoms (eg, diarrhea and fatigue) are common in the general population, we focused on symptoms leading to health care contact as indicators of symptom severity. Population-based studies on the prevalence of symptoms after Roux-en-Y gastric bypass (RYGB) surgery are sparse. In total, 1219 of 1394 (87.4%) patients felt better or much better and 113 (8.1%) reported reduced well-being after RYGB surgery (Figure).  M, Barancelli A 54-year-old nurse with a long-standing history of obesity, with a maximum weight of 237 pounds and body mass index (BMI) of 42 kg/m2, had laparoscopic Roux-en-Y gastric bypass (RYGB) 9 years before presentation.  JT, Wang  KM, Armstrong Prevalence and severity (based on contacts with health care system, ranging from no contact to hospitalization) of self-reported symptoms following RYGB surgery.  F, eCollection 2020 Jun. Population-based studies on the prevalence of symptoms after Roux-en-Y gastric bypass (RYGB) surgery are sparse. Nonrespondents tended to be younger, but the age distribution differed only by a few percentage points, not comprising a risk of bias (eTable 3 in the Supplement). Based on the SF-12, the median MCS was 41.8 (IQR, 34.8-45.9) for patients who underwent RYGB surgery and 39.7 (IQR, 31.7-44.7) in the comparison cohort.  M, Gesten Statistical analysis: Gribsholt, Pedersen.  V, Sunde  et al.  M, Näslund Conflict of Interest Disclosures: None reported. Comparison of Self-Reported Data on Kidney Stones and Gallstones With the Gold Standard in the Danish National Patient Registry, eTable 3.  R, Jonas 2013 Jan;23(1):24-30. doi: 10.1007/s11695-012-0735-8.  MF. Our website uses cookies to enhance your experience. -, J Am Coll Surg. Costs of Gastric Bypass Surgery Gastric Bypass Surgery Reference Magro D, Geloneze B, Delfini R, Pareja B, Callejas F, Pareja J. Most patients reported improved well-being after RYGB surgery, but the prevalence of symptoms was high and nearly one-third of patients were hospitalized, 4- to 5-fold more than among the comparison group.  T; Obesity Surgery Working Group; Competence Network Obesity. On June 8, 2015, a comparison cohort of 89 individuals who did not undergo RYGB surgery and who were matched with patients according to sex and body mass index were recruited via the Internet; this cohort also responded to the questionnaire.  L, O’Dwyer sign up for alerts, and more, to access your subscriptions, sign up for alerts, and more, to download free article PDFs, sign up for alerts, customize your interests, and more, to make a comment, download free article PDFs, sign up for alerts and more, Archives of Neurology & Psychiatry (1919-1959), https://www.retsinformation.dk/forms/r0710.aspx?id=137674#Kap4, FDA Approval and Regulation of Pharmaceuticals, 1983-2018, Global Burden of Skin Diseases, 1990-2017, Health Care Spending in the US and Other High-Income Countries, Life Expectancy and Mortality Rates in the United States, 1959-2017, Medical Marketing in the United States, 1997-2016, Practices to Foster Physician Presence and Connection With Patients in the Clinical Encounter, US Burden of Cardiovascular Disease, 1990-2016, US Burden of Neurological Disease, 1990-2017, Waste in the US Health Care System: Estimated Costs and Potential for Savings, Register for email alerts with links to free full-text articles. doi: 10.1097/PRS.0b013e3181772aa8. Only 63.7% of patients completed the questionnaire. Five-Year Outcomes of Gastric Bypass In this study of bariatric surgery, adolescents and adults showed marked weight loss that was similar in magnitude in the two groups 5 years after surgery…  PD, Pinching Excess skin problems among adolescents after bariatric surgery.  Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity.Â, Schauer  B.  A novel distal very long Roux-en Y gastric bypass (DVLRYGB) as a primary bariatric procedure—complication rates, weight loss, and nutritional/metabolic changes in the first 355 patients.Â, Raoof A total of 1429 patients undergoing RYGB surgery (63.7%) responded to the survey; 286 (20.0%) were male.  PR, Jackson  S, Medbery 2007 May-Jun;38(3):103-4. Development of weight loss procedures with fewer subsequent symptoms should be a high priority.  G, Herrera The vast majority of patients reported better or much better well-being after RYGB surgery. Those studies included different symptoms,20,21,23 examined 30-day complication rates,23 or only examined hospitalizations.20,21 After restricting our study to care received in the hospital, the association with younger age persisted (eTable 1 in the Supplement).  DA, Talamini  Six-year changes in health-related quality of life in gastric bypass patients versus obese comparison groups.Â, Julia To examine patients’ overall well-being and the prevalence and predictors of medical, nutritional, and surgical symptoms after RYGB surgery, and their association with quality of life.  A, Olbers  Effect of marital status on treatment and survival of extremity soft tissue sarcoma.Â, Tapia Granados Fifty-three patients (21%) have undergone a total of 61 body contouring … Aspiration Pneumonia: a Shadow in Post-Bariatric Patient : Correlation between aspiration and minigrastric bypass. Results  Obesity continues to increase in prevalence worldwide. The short- to mid-term symptom prevalence of dumping syndrome after primary gastric-bypass surgery and its impact on health-related quality of … eFigure 1. Of 2238 patients undergoing RYGB surgery, 1429 (63.7%) responded to the survey.  P.  Predictors of gallstone formation after bariatric surgery: a multivariate analysis of risk factors comparing gastric bypass, gastric banding, and sleeve gastrectomy [published correction appears in, Shiffman Mitchell JE, Crosby RD, Ertelt TW, Marino JM, Sarwer DB, Thompson JK, Lancaster KL, Simonich H, Howell LM.  et al. Presence of symptoms prior to RYGB surgery was also queried. Importance  Our results are consistent with the prevalences reported in studies regarding severe dumping, anemia, kidney stones, gallstones, and neurologic symptoms.6-11,14-17,36-39 Dumping may, however, be an integrated part of the effect of RYGB surgery in inducing weight loss.  E, Rasmussen  MD, Martin Objectives  2016;151(6):504–511. Mean age at the time of the survey was 47.1 years (range, 26.9-68.0 years); the current median body mass index (calculated as weight in kilograms divided by height in meters squared) was 29.7, corresponding to a median total weight loss of 35.7%. Nearly one-third of patients had been admitted to a hospital owing to these symptoms, mainly surgical symptoms.  JR.  Anemia after bariatric surgery cannot be explained by iron deficiency alone: results of a large cohort study.Â, Vargas-Ruiz Mean age at the time of the survey was … In this cohort, the prevalence of AUD was greater in the second postoperative year than the year prior to surgery or in the first postoperative year and was … Of all patients, 74% desire a body contouring surgery after gastric bypass surgery. -, Am J Surg. Focus on the QoL among patients with many symptoms may be required since such patients are at risk of depression. Symptoms after RYGB surgery were reported by 1266 patients (88.6%); 966 patients (67.6%) had been in contact with the health care system about their symptoms vs 31 [34.8%] of those in the comparison group, and 416 (29.1%) had been hospitalized vs 6 [6.7%] of those in the comparison group. Most patients reported a better or much better well-being after surgery despite a high prevalence of symptoms.  K, Morton The symptoms most commonly reported among patients who underwent RYGB surgery were fatigue (776 [54.3%]), dumping (749 [52.4%]), and abdominal pain (778 [54.4%]).  T, Näslund Prevalence and severity (based on contacts with health care system, ranging from no contact to hospitalization) of self-reported symptoms following RYGB surgery. Development of weight loss procedures with fewer subsequent symptoms should be a high priority. 2008 Oct;18(10):1308-12. doi: 10.1007/s11695-008-9557-0. These symptoms have generally been classified as surgical or medical and nutritional depending on the primary treatment procedures.  NK,  PJ. Of the patients reporting dumping, 494 (66.0%) also reported abdominal pain. A total of 1219 of 1394 patients (87.4%) felt better or much better than before RYGB surgery, while 113 of 1394 (8.1%) felt worse than before surgery.  E, Sandegaard Researchers from the Geisinger Health System followed nearly 2,700 patients who had gastric bypass at the system's nationally accredited bariatric … The rate increased significantly by age in the 2 younger age categories but most notably among people aged 25 to 64 years: from … Cuomo R, Giardino FR, Nisi G, Brandi C, Zerini I, Voglino C, Gaggelli I, Grimaldi L. Obes Surg.  I, Ehrenstein Quality of life was inversely associated with the number of symptoms (. We presented graphically the overall well-being of patients who underwent RYGB surgery and calculated symptom prevalence according to this factor. We also included a question addressing current well-being compared with well-being before RYGB surgery. Obes Surg. For each symptom that occurred after RYGB surgery, we asked patients if the symptom had led to any contact with the health care system, categorizing patients as follows: 1, no contact; 2, any contact (including contact with general practitioner, visit in outpatient specialty clinic, and hospital admission); 3, contact with secondary care only (visit in outpatient specialty clinic and hospital admission); and 4, hospital admission (eFigure 2 in the Supplement). , Huber O, Chilcott M, Pittet-Cuénod B. Obes Surg JH, Gorman JH... Prevalence according to this factor identified a higher prevalence of symptoms after RYGB surgery patients undergoing surgery. Because hypoglycemia consists of unspecific symptoms, patients with many symptoms may be required since such patients are undergoing contouring. 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